Methodolatry. You’re describing methodolatry, or the obscene worship of the randomized clinical trial as the only valid method of clinical investigation.
Shouting “randomized trials” is grade-school evidence based medicine. If you can’t make decisions based on data from natural experiments, quasi-experimental trials, and well-designed observational studies, you should just sit the pandemic out. 850,000 deaths is serious business
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And if you want to see a classic example of methodolatry gone amok, I present...Dr. Vinay Prasad!
Replying to @MDaware
thanks for listing all the trials you havent conducted
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That one about "zero randomized trials of masking in wealthy nations" is a beaut, too. He *knows* that there have been randomized trials of masking in more impoverished nations that showed that masking works to slow the spread of #COVID19. He's moving the goalposts.

Jan 18, 2022 · 9:09 PM UTC

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Replying to @gorskon
I also like "zero randomized trials of masking post-vaccine." Wouldn't it be wildly unethical to conduct such a survey since we have randomized control trials of masks and vaccines separately?
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Replying to @gorskon
Imagine approaching nursing homes and or IRBs for a trial of cohorting.
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Replying to @gorskon
If a randomized trial IS done in a wealthy country, it will be, "zero randomized trials of masking in wealthy nations in households with 2+ automobiles and at least 1 pet."
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Replying to @gorskon
Well ... what does it matter if impoverished nations don't mask up as long as they still have enough subjects alive to assemble our ridiculously underpriced idontcarePhones?
Replying to @gorskon
GIF